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http://hdl.handle.net/11452/34227
Title: | Platelet function and fibrinolytic activity in juvenile swimmers |
Authors: | İnce, Elif Uludağ Üniversitesi/Spor Bilimleri Fakültesi. Şahin, Şenay IHS-7375-2023 27867938700 |
Keywords: | Chemistry Platelet function Platelet activity Physical activity Swimmers Aerobic exercise Angina-pectoris Coagulation |
Issue Date: | 2016 |
Publisher: | Scibulcom |
Citation: | Şahin, Ş. ve İnce, E. (2016). "Platelet function and fibrinolytic activity in juvenile swimmers". Oxidation Communications, 39(4), Part 1, 3199-3205. |
Abstract: | Participation in regular physical activity reduces the risk of developing diabetes, cardiovascular and other lifestyle-dependent diseases. Interestingly, acute and strenuous exercise influences platelet function and platelet leukocyte interaction as well as blood coagulation and fibrinolysis. However, the underlying mechanisms of these interactions are still completely understood. Accordingly, in the present study we investigated the effect of High-intensity endurance competition (HIC) on platelet function and activity. In addition, we investigated also effects of blood lactate (BLa) on platelet function.40 healthy (20 male, 20 female) volunteer juvenile swimmers aged 12-13 years performed strenuous exercises at 100% of BLa which corresponded to about 80% of peak oxygen consumption (peak VO2). Blood samples were taken after 30 min rest and immediately after exercise and after 30 min rest.All parameters after exercise were significantly higher than those of before exercise and recovery period. Recovery PF4, PAI-1 and t-PA levels also were significanlty increased than before exercise levels. In conclusion, the effect of the acute arm exercise on platelet aggregation depends on the intensity of exercise and the sensitivity of the membrane and intracellular signalling pathways of platelets. Exercise-induced platelet aggregation occurred without an increase in ATP release. The haemodynamic changes after the exercises, result in an increased shear rate, the increase after strenuous exercise is more pronounce. Therefore, it is recommended that submaximum endurance performance should be individually developed in order for everyone to be able to carry out normal daily activities and also to exercise well below the IAT. |
URI: | http://hdl.handle.net/11452/34227 |
ISSN: | 0209-4541 |
Appears in Collections: | Scopus Web of Science |
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