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Başlık: Association of monocyte to HDL cholesterol level with contrast induced nephropathy in STEMI patients treated with primary PCI
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.
0000-0002-8974-8837
0000-0001-8404-8252
0000-0002-1953-7735
Sağ, Salim
Yıldız, Abdülmecit
Aydın, Kaderli Aysel
Gül, Bülent Cuma
Bedir, Ömer
Ceǧilli, Ercan
Özdemir, Bülent
Can, Fatma Ezgi
Aydınlar, Ali
AAI-6632-2021
AAW-9185-2020
12140008100
57192158999
7801322152
57140207000
57191868066
57144621700
7004168959
56689608500
57192164890
Anahtar kelimeler: Medical laboratory technology
Contrast induced nephropathy
HDL-cholesterol
Monocyte
Percutaneous coronary intervention
Acute kidney injury
High-density-lipoprotein
Elevation myocardial-infarction
Creatinine clearance ratio
Primary angioplasty
Cardiovascular events
N-acetylcysteine
Renal-function
Risk score
Yayın Tarihi: 18-May-2016
Yayıncı: Walter de Gruyter
Atıf: Sağ, S. vd. (2017). ''Association of monocyte to HDL cholesterol level with contrast induced nephropathy in STEMI patients treated with primary PCI''. Clinical Chemistry and Laboratory Medicine, 55(1), 132-138.
Özet: Background: Contrast induced nephropathy (CIN) has been proven to be a clinical condition related to adverse cardiovascular outcomes. In recent studies, the monocyte to high density lipoprotein ratio (MHR) has been-postulated as a novel parameter associated with adverse renal and cardiovascular outcomes. In this study we-investigated the association of MHR with CIN in-ST-segment elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI). Methods: Consecutive STEMI patients treated with primary PCI were prospectively recruited. Subjects were categorized into two groups; as patients who developed CIN (CIN+) and patients who did not develop CIN (CIN-) during hospitalization. CIN was defined as either a 25% increase in serum creatinine from baseline or 44.20 mu mol/L increase in absolute value, within 72 h of intravenous contrast administration. Results: A total number of 209 patients were included in the study. Thirty-two patients developed CIN (15.3%). In the CIN (+) patients, monocytes were higher [1.02 (0.83-1.39) vs. 0.69 (0.53-0.90) 109/L, p < 0.01] and HDL cholesterol levels were lower [0.88 (0.78-1.01) vs. 0.98 (0.88-1.14) mmol/L, p < 0.01]. In addition, MHR was significantly higher in the CIN (+) group [1.16 (0.89-2.16) vs. 0.72 (0.53-0.95) 10(9)/mmol, p < 0.01]. In multivariate logistic regression analysis, MHR, Mehran score, AGEF score and CV/eGFR were independently correlated with CIN. Conclusions: Higher MHR levels may predict CIN development after primary PCI in STEMI patients.
URI: https://doi.org/10.1515/cclm-2016-0005
https://www.degruyter.com/document/doi/10.1515/cclm-2016-0005/html
1437-4331
http://hdl.handle.net/11452/30143
ISSN: 1434-6621
Koleksiyonlarda Görünür:Scopus
Web of Science

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