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http://hdl.handle.net/11452/29860
Başlık: | Expressions of endocan in patients with meningiomas and gliomas |
Yazarlar: | Atukeren, Pınar Kunbaz, Ahmad Türk, Okan Kemerdere, Rahsan Ulu, Mustafa Onur Tanrıverdi, Taner Uludağ Üniversitesi/Tıp Fakültesi/Adli Tıp Anabilim Dalı. 0000-0002-4047-6455 İnanır, Nursel Türkmen 57188706721 |
Anahtar kelimeler: | Biotechnology & applied microbiology Genetics & heredity Research & experimental medicine Pathology Cell-specific molecule-1 Marker Esm-1 Survival Invasion Cancer |
Yayın Tarihi: | 30-Haz-2016 |
Yayıncı: | Hindawi |
Atıf: | Atukeren, P. vd. (2016). "Expressions of endocan in patients with meningiomas and gliomas". ed. Lance A. L. Disease Markers, 2016. |
Özet: | Objective. Endocan has been shown to be a marker for several cancers and may show degree of malignancy. The aim of this study is to assess tissue levels of endocan in common brain tumors, namely, meningiomas, low-grade gliomas (LGGs), and high-grade gliomas (HGGs). Patients and Methods. Endocan was assayed by commercially available enzyme linked immunosorbent assay (ELISA) kits in a total of 50 brain tumors (20 meningiomas, 19 LGGs, and 20 HGGs) and 15 controls. The results were compared to control brain tissues. Results. Each tumor group showed significant higher levels of endocan compared to controls (p < 0.05). In addition, endocan levels showed steady increase from the least (meningiomas) to the most (HGGs) malignant tumors and positive correlation was noted between the degree of malignancy and endocan level (p = 0.0001). Conclusion. Endocan, a vital molecule for angiogenesis, is expressed in common brain tumors and results suggest that endocan could be a marker for malignancy. |
URI: | https://doi.org/10.1155/2016/7157039 https://www.hindawi.com/journals/dm/2016/7157039/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978841/ http://hdl.handle.net/11452/29860 |
ISSN: | 0278-0240 1875-8630 |
Koleksiyonlarda Görünür: | Scopus Web of Science |
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