Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/29649
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dc.contributor.authorWebber, Mark A.-
dc.contributor.authorPiddock, Laura J. V.-
dc.date.accessioned2022-12-02T07:09:43Z-
dc.date.available2022-12-02T07:09:43Z-
dc.date.issued2015-10-22-
dc.identifier.citationŞahintürk, P. vd. (2016). "High level fluoroquinolone resistance in Escherichia coli isolated from animals in Turkey is due to multiple mechanisms". Turkish Journal of Veterinary and Animal Sciences, 40(2), 214-218.tr_TR
dc.identifier.issn1300-0128-
dc.identifier.urihttps://doi.org/10.3906/vet-1506-74-
dc.identifier.urihttps://journals.tubitak.gov.tr/veterinary/vol40/iss2/14/-
dc.identifier.urihttp://hdl.handle.net/11452/29649-
dc.description.abstractThe aim of this study was to determine the molecular mechanisms of fluoroquinolone resistance in E. coli isolated from cattle, goats, sheep, cats, and dogs in Turkey. Twenty nonreplicate E. coli isolates (chosen on the basis of RAPD pattern) from food-producing animals were selected for the study. To identify phenotypic differences between isolates, the sum of the MIC values of 14 antimicrobials was calculated; values ranged from 565 to 2520 mu g/mL, indicating the diversity in antimicrobial resistance present in the panel of isolates. PCR and qRT-PCR were used to characterize the presence and expression levels of known molecular mechanisms of fluoroquinolone resistance. The number of E. coli isolates having single, double, and triple topoisomerase mutations was 2, 10, and 5, respectively. Moreover, the number of qnrA -, qnrS -, oqxB -, and aac(6') Ib-cr-containing E. coli isolates was 1, 4, 1, and 17, respectively. Increased expression of acrB and soxS was detected in 2 and 9 isolates, respectively. The results of this study show a wide range of different mechanisms of fluoroquinolone resistance in E. coli isolates in Turkey.en_US
dc.description.sponsorshipEuropean Cooperation in Science and Technology (COST) - BM0701en_US
dc.language.isoenen_US
dc.publisherTÜBİTAKtr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAtıf Gayri Ticari Türetilemez 4.0 Uluslararasıtr_TR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectVeterinary sciencesen_US
dc.subjectFluoroquinolone resistanceen_US
dc.subjectE. colien_US
dc.subjectAnimalsen_US
dc.subjectPCRen_US
dc.subjectqRT-PCRen_US
dc.subjectMediated quinolone resistanceen_US
dc.subjectAntibiotic-resistanceen_US
dc.subjectSalmonellaen_US
dc.subjectPrevalencetr_Ten_USR
dc.subjectEffluxen_US
dc.subjectGenesen_US
dc.subjectOqxaben_US
dc.titleHigh level fluoroquinolone resistance in Escherichia coli isolated from animals in Turkey is due to multiple mechanismsen_US
dc.typeArticleen_US
dc.identifier.wos000369159000014tr_TR
dc.identifier.scopus2-s2.0-84957596806tr_TR
dc.relation.tubitakTOVAG-110O478en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Moleküler Farmakoloji Laboratuvarı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Mikrobiyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü.tr_TR
dc.contributor.orcid0000-0003-4337-577Xtr_TR
dc.contributor.orcid0000-0001-9018-1842tr_TR
dc.contributor.orcid0000-0002-9212-8743tr_TR
dc.identifier.startpage214tr_TR
dc.identifier.endpage218tr_TR
dc.identifier.volume40tr_TR
dc.identifier.issue2tr_TR
dc.relation.journalTurkish Journal of Veterinary and Animal Sciencesen_US
dc.contributor.buuauthorŞahintürk, Pınar-
dc.contributor.buuauthorArslan, Erdem-
dc.contributor.buuauthorBüyükcangaz, Esra-
dc.contributor.buuauthorSonal, Songül-
dc.contributor.buuauthorŞen, Ayşin-
dc.contributor.buuauthorErsoy, Figen-
dc.contributor.buuauthorCengiz, Murat-
dc.contributor.researcheridABE-5935-2020tr_TR
dc.contributor.researcheridAAI-6817-2021tr_TR
dc.contributor.researcheridAAL-2323-2020tr_TR
dc.contributor.researcheridABI-4237-2020tr_TR
dc.contributor.researcheridAAH-1820-2021tr_TR
dc.contributor.researcheridK-3299-2019tr_TR
dc.relation.collaborationYurt dışıtr_TR
dc.indexed.trdizinTrDizintr_TR
dc.subject.wosVeterinary sciencesen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.wos.quartileQ3en_US
dc.contributor.scopusid55342852700tr_TR
dc.contributor.scopusid55236738400tr_TR
dc.contributor.scopusid25649139400tr_TR
dc.contributor.scopusid7801642676tr_TR
dc.contributor.scopusid7401592869tr_TR
dc.contributor.scopusid55088196700tr_TR
dc.contributor.scopusid16635026700tr_TR
dc.subject.scopusEscherichia Coli; Plasmids; Enterobacteriaceaeen_US
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