Bu öğeden alıntı yapmak, öğeye bağlanmak için bu tanımlayıcıyı kullanınız: http://hdl.handle.net/11452/29236
Başlık: Characterization of migraineurs having allodynia results of a large population-based study
Yazarlar: Baykan, Betül
Ekizoğlu, Esme
Orhan, Elif Kocasoy
Saip, Sabahattin
Siva, Aksel
Ertaş, Mustafa
Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı.
Karlı, Necdet
Zarifoğlu, Mehmet
6506587942
6603411305
Anahtar kelimeler: Anesthesiology
Neurosciences & neurology
Migraine
Headache
Allodynia
Cutaneous allodynia
Spreading depression
Association
Headache
Features
Sex
Yayın Tarihi: 8-Eyl-2015
Yayıncı: Lippincott Williams & Wilkins
Atıf: Baykan, B. vd. (2016). "Characterization of migraineurs having allodynia results of a large population-based study". Clinical Journal of Pain, 32(7), 631-635.
Özet: Objective: Allodynia reflects the clinical correlate of central sensitization, but it is usually neglected in clinical headache management. We aimed to report the prevalence and previously unnoticed associations of allodynia in migraineurs by a nationwide face-to-face questionnaire-based study by physicians. Methods: A total of 5323 households were examined for headache according to the diagnostic criteria of International Classification of Headache Disorders-II. Detailed headache features, premonitory signs, demographics, socio-economic status, and hormonal status of female individuals were analyzed with regard to the presence of allodynia in patients with definite migraine. Results: Allodynia was present in 61.1% of migraineurs in the general population of Turkey. The duration and severity of attacks (P < 0.0001), photophobia (P = 0.001), phonophobia, and also osmophobia (P < 0.0001), as well as premonitory signs (P = 0.018), showed significant associations with allodynia. Migraineurs with aura or family history of migraine more often reported allodynia in comparison with those without (P = 0.001 and 0.028, respectively). Allodynic migraineurs had a higher rate of physician consults and high levels on the Migraine Disability Assessment questionnaire, reflecting increased burden of headache. Furthermore, migraineurs with allodynia had high probability of attacks close to menses. Migraine improved during pregnancy, but it worsened after menopause or during oral contraceptive use in individuals experiencing allodynia when compared with those without allodynia. Discussion: The duration, severity, and disability of migraine attacks, photophobia, phonophobia, and osmophobia, as well as premonitory signs, showed significant associations with allodynia in the general population. Moreover, migraineurs with aura or family history of migraine more often reported allodynia, and allodynic migraneurs were more sensitive to hormonal changes. Allodynia, which seems to indicate higher tendency to central sensitization, should be implemented in daily headache practice to predict the prognosis and high levels of migraineous involvement.
URI: https://doi.org/10.1097/AJP.0000000000000301
https://journals.lww.com/clinicalpain/Fulltext/2016/07000/Characterization_of_Migraineurs_Having_Allodynia_.11.aspx
http://hdl.handle.net/11452/29236
ISSN: 0749-8047
1536-5409
Koleksiyonlarda Görünür:Scopus
Web of Science

Bu öğenin dosyaları:
Bu öğeyle ilişkili dosya bulunmamaktadır.


DSpace'deki bütün öğeler, aksi belirtilmedikçe, tüm hakları saklı tutulmak şartıyla telif hakkı ile korunmaktadır.