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Başlık: Invasive fungal infections in renal transplant recipients: Epidemiology and risk factors
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji ve Enfeksiyon Hastalıkları Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Nefroloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.
0000-0002-4803-8206
0000-0002-0710-0923
Şahin, Sezin Zorlu
Akalın, Halis
Ersoy, Alparslan
Yıldız, Abdulmecit
Ocakoğlu, Gökhan
Çetinoğlu, Ezgi Demirdöven
Dizdar, Oğuzhan Sıtkı
Kazak, Esra
Ener, Beyza
AAG-8459-2021
AAG-8523-2021
AAH-5180-2021
AAH-5054-2021
AAU-8952-2020
56537830100
57207553671
35612977100
56256977500
15832295800
57189524206
55202193000
24921238200
15053025300
Anahtar kelimeler: Candida infections
Fungal infection
Invasive aspergillosis
Kidney transplantation
Cryptococcus-neoformans
Candida-albicans
Aspergillosis
Calcineurin
Galactomannan
Mortality
Complications
Zygomycosis
Virulence
Mycology
Aspergillus
Candida
Cytomegalovirus
Yayın Tarihi: Ağu-2015
Yayıncı: Springer
Atıf: Şahin, S. Z. vd. (2015). "Invasive fungal infections in renal transplant recipients: Epidemiology and risk factors". Mycopathologia, 180(1-2), 43-50.
Özet: Invasive fungal infections are a major cause of morbidity and mortality among renal transplant recipients. The aim of this study was to investigate the frequency and risk factors for fungal infections in renal transplant recipients. We retrospectively evaluated all kidney transplant recipients at our center from December 1988 to June 2010 for the epidemiology, spectrum, risk factors, and mortality of invasive fungal infections. In 32 patients (10.30 %), at least one fungal infection developed after the transplantation. The most common pathogens causing fungal infections in our patients were Candida spp. and Aspergillus spp. The independent risk factors associated with invasive fungal infection episodes were antibiotic treatment within the last 3 months (OR 15.88, 95 % CI 3.90-64.73, p < 0.001), cytomegalovirus infection (OR 18.54, 95 % CI 9.01-38.17, p < 0.001), and the presence of diabetes mellitus (OR 6.01, 95 % CI 2.95-12.25, p < 0.001). Mortality was significantly higher among patients with fungal infections than among other patients (53.10 and 17.80 %, respectively; p < 0.001). It is difficult to diagnose and treat fungal infections early, and it can be useful to determine independent risk factors in order to identify and treat high-risk patients.
URI: https://doi.org/10.1007/s11046-015-9875-4
https://link.springer.com/article/10.1007/s11046-015-9875-4
http://hdl.handle.net/11452/27142
ISSN: 0301-486X
Koleksiyonlarda Görünür:Scopus
Web of Science

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