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Başlık: Clinical course of hyperprolactinemia in children and adolescents: A review of 21 cases
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Pediatrik Endokrinoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı
0000-0003-0710-5422
0000-0002-1684-1053
Eren, Erdal
Yapıcı, Senay
Çakır, Esra Deniz Papatya
Ceylan, Latife Aytekin
Saǧlam, Halil
Tarım, Ömer Faruk
C-7392-2019
AAH-1155-2021
AAM-1734-2020
36113153400
44161566600
37003613900
40461059700
35612700100
6701427186
Anahtar kelimeler: Endocrinology & metabolism
Pediatrics
Prolactin
Puberty
Prolactinoma
Pituitary
Yayın Tarihi: Haz-2011
Yayıncı: Galenos Yayıncılık
Atıf: Eren, E. vd. (2011). "Clinical course of hyperprolactinemia in children and adolescents: A review of 21 cases". Journal of Clinical Research in Pediatric Endocrinology, 3(2), 65-69.
Özet: Objective: Hyperprolactinemia may be due to various etiological factors and may present with different signs and symptoms. It is relatively less frequent in childhood than in adulthood. The aim of this study was to evaluate retrospectively the clinical course and outcome of hyperprolactinemia in pediatric patients. Methods: We investigated the records of 21 patients with hyperprolactinemia who attended a tertiary hospital. Results: Menstrual problems, galactorrhea, and headache were the most common presenting symptoms. Hyperprolactinemia was due to microadenoma in 10, macroadenoma in 7, and was drug-induced in 4 patients. Bromocriptine and cabergoline were equally effective in lowering serum prolactin levels. Surgical treatment in children with macroprolactinoma was not curative and dopamine agonist therapy was required postoperatively. Conclusion: In the presence of any clinical symptom or sign suggestive of suppression of the pituitary-gonadal axis, hyperprolactinemia should not be forgotten as a probable diagnosis. Medical therapy seems effective in microadenoma. Surgical therapy may not be successful in macroadenoma and recurrence is frequent.
URI: https://doi.org/10.4274/jcrpe.v3i2.14
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119443/
http://hdl.handle.net/11452/23218
ISSN: 1308-5727
1308-5735
Koleksiyonlarda Görünür:Scopus
Web of Science

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