Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/33831
Title: A Retrospective evaluation of the incidence and risk factors of nosocomial diarrhea in critically ill adult patients
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji ve Enfeksiyon Hastalıkları Anabilim Dalı.
0000-0001-8111-5958
0000-0003-4820-2288
Özgür, Mustafa
Girgin, Nermin Kelebek
Akalın, Halis
İşçimen, Remzi
Sınırtaş, Melda
Kahveci, Ferda
AAI-8104-2021
AAG-9356-2021
AAH-7250-2019
HKP-2533-2023
AAU-8952-2020
55846946000
55663009300
57207553671
16645821200
6505818048
6602405968
Keywords: General & internal medicine
Nosocomial diarrhea
Intensive care
Critically ill
Enteral feeding
Clostridium difficile infection
Clostridium-difficile infection
Intensive-care-unit
Gastrointestinal complications
Antibiotics
Multicenter
Symptoms
Issue Date: 2-Jan-2016
Publisher: Carbone Editore
Citation: Özgür, M. vd. (2016). "A Retrospective evaluation of the incidence and risk factors of nosocomial diarrhea in critically ill adult patients". Acta Medica Mediterranea, 32(3), 741-746.
Abstract: Introduction: Diarrhea is a commonly encountered complication in critically ill patients. It causes fluid and electrolyte loss, increases the workload of nurses, and prolongs the duration of hospitalization. The aim of this retrospective study was to investigate the incidence and risk factors associated with nosocomial diarrhea in adult patients treated in intensive care unit (ICU). Materials and methods: Records of 786 adult patients treated in the ICU between January 2004 and May 2009 were inspected retrospectively. Loose or watery stools occurring three times a day and more was considered as diarrhea. The control group included those patients who were treated in ICU at the same time as the patients with diarrhea, with similar demographic and clinic features. Results: It was established that of 786 patients, 78 (9.92%) developed diarrhea. The time lapse between admission to the ICU and the onset of diarrhea was 12.41 +/- 21.7 days, and the duration of diarrhea was 438 +/- 2.13 days. Compared to the control's (n=80), the rate of enteral feeding was higher in patients with diarrhea, enteral nutrition products of high concentration, proton pump inhibitors, medications containing sorbitol and Mg+2, clindamycin, and cephalosporins were used significantly more often (p=0.002, p=0.006, p=0.048, p=0.006, p=0.033, p=0.048). Furthermore, the length of stay in ICU was longer in these patients (p=0.043). Clostridium difficile toxin was determined to be positive in 11 patients with diarrhea (14.1%). These cases were older and had a longer ICU stay and duration of diarrhea (p=0.031, p=0.027, p=0.004). Conclusion: It was found that the patients with diarrhea had a high enteral nutrition infusion rate, and products concentration, a high level of drug usage such as proton pump inhibitors, antibiotics, and sorbitol, and a low albumin level. Nosoconzial diarrhea could also prolong the length of ICU stay in critically ill patients.
URI: https://doi.org/10.19193/0393-6384_2016_3_83
http://hdl.handle.net/11452/33831
ISSN: 0393-6384
2283-9720
Appears in Collections:Scopus
Web of Science

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