1. Açık Erişim@BUU
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Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/27789
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dc.contributor.authorBridoux, Alexandre-
dc.contributor.authorCui, Huadong-
dc.contributor.authorDyskin, Evgeny-
dc.contributor.authorSchmitzer, Andreea Ruxandra-
dc.contributor.authorMousa, Shaker A.-
dc.date.accessioned2022-07-07T10:23:21Z-
dc.date.available2022-07-07T10:23:21Z-
dc.date.issued2010-06-01-
dc.identifier.citationBridoux, A. vd. (2010). "Semisynthesis and pharmacological activities of thyroxine analogs: Development of new angiogenesis modulators". Bioorganic and Medicinal Chemistry Letters, 20(11), 3394-3398.en_US
dc.identifier.issn0960-894X-
dc.identifier.issn1464-3405-
dc.identifier.urihttps://doi.org/10.1016/j.bmcl.2010.04.011-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0960894X10004713-
dc.identifier.urihttp://hdl.handle.net/11452/27789-
dc.description.abstractNovel thyroxine analogs with hindered phenol, amino and carboxylic acid groups have been synthesized and the effects of the synthesized compounds on angiogenesis using the chick chorioallantoic membrane and mouse matrigel models have been tested. Pharmacological profiles revealed that thyroxine tolerates numerous modifications on the amino group and remains active. These results provide the rationale for the selection of a novel thyroxine nanoparticle precursor.en_US
dc.description.sponsorshipCharitable Leadership Foundationen_US
dc.description.sponsorshipMedical Technology Acceleration Programen_US
dc.description.sponsorshipPharmaceutical Research Instituteen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Scienceen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectThyroxineen_US
dc.subjectEsterificationen_US
dc.subjectSilylationen_US
dc.subjectUV-visen_US
dc.subjectAngiogenesisen_US
dc.subjectNanopharmaceutical technologyen_US
dc.subjectExtracelluler segmenten_US
dc.subjectCrystal-structureen_US
dc.subjectThyhroid-hormoneen_US
dc.subjectForce-fielden_US
dc.subjectProteinsen_US
dc.subjectPharmacology & pharmacyen_US
dc.subjectChemistryen_US
dc.subject.meshAngiogenesis inhibitorsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshChick embryoen_US
dc.subject.meshMiceen_US
dc.subject.meshModels, molecularen_US
dc.subject.meshThyroxineen_US
dc.titleSemisynthesis and pharmacological activities of thyroxine analogs: Development of new angiogenesis modulatorsen_US
dc.typeArticleen_US
dc.identifier.wos000277788900043tr_TR
dc.identifier.scopus2-s2.0-77953293160tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Veterinerlik Fakültesi/Temel Bilimler Bölümü.tr_TR
dc.contributor.orcid0000-0002-5600-8162tr_TR
dc.identifier.startpage3394tr_TR
dc.identifier.endpage3398tr_TR
dc.identifier.volume20tr_TR
dc.identifier.issue11tr_TR
dc.relation.journalBioorganic and Medicinal Chemistry Lettersen_US
dc.contributor.buuauthorYalçın, Murat-
dc.contributor.researcheridAAG-6956-2021tr_TR
dc.relation.collaborationYurt dışıtr_TR
dc.identifier.pubmed20434332tr_TR
dc.subject.wosChemistry, medicinalen_US
dc.subject.wosChemistry, organicen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ2en_US
dc.contributor.scopusid57192959734tr_TR
dc.subject.scopusTetraiodothyroacetic Acid; Thyroid Hormones; Nano-Diamino-Tetracen_US
dc.subject.emtreeAmino aciden_US
dc.subject.emtreeAngiogenesis inhibitoren_US
dc.subject.emtreeMatrigelen_US
dc.subject.emtreeThyroxine derivativeen_US
dc.subject.emtreeAngiogenesisen_US
dc.subject.emtreeAnimal experimenten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeChicken_US
dc.subject.emtreeChorioallantoisen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDrug activityen_US
dc.subject.emtreeDrug effecten_US
dc.subject.emtreeDrug synthesisen_US
dc.subject.emtreeDrug tolerabilityen_US
dc.subject.emtreeMouseen_US
dc.subject.emtreeNonhumanen_US
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