Sağlıklı çocuklarda idrar kalsiyum atılımı

Abstract

Aim: Measurement of calcium/creatinine ratio in spot urine sample is a practical screening method for hypercalciuria. This study aimed to identify age related reference percentile values for urinary calcium/creatinine ratio in healthy children and to determine the frequency of hypercalciuria.

Material and Method: A total of 614 children were included. Second morning urine samples were collected and calcium/creatinine ratio (mg/mg) was calculated Results were examined for the following six age groups. Group 1, 1-6 months; Group 2, 7-12 months, Group 3, 13 months-2 years; Group 4, 25 months-6 years; Group 5, 7-12 years, and Group 6, 13-16 years.

Results: The mean +/- SD values for calcium/creatinine ratios of the age groups were as follows Group 1,033 +/- 0.10, Group 2,0.23 +/- 0 06; Group 3, 0.15 +/- 0.08; Group 4, 0 13 +/- 0.08, Group 5, 0.09 +/- 0 07; and Group 6, 0.08 +/- 0.07, respectively Corresponding 95th percentile values for the age groups 1 to 6 were 0.57, 0 40, 0.32, 0.26, 0.23, and 0.23, respectively. Hypercalciuria prevalence was found as 4.7% in our area Urinary calcium/creatinine ratio was negatively correlated with age and body mass index.

Conclusions: Our findings suggest that age of the child, 95th percentile values and geographical differences should be taken into account in detecting the reference values for urinary calcium/creatinine ratio.