Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/22692
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dc.date.accessioned2021-11-17T11:36:47Z-
dc.date.available2021-11-17T11:36:47Z-
dc.date.issued2010-01-
dc.identifier.citationHakyemez, B. vd. (2010). "Solitary metastases and high-grade gliomas: radiological differentiation by morphometric analysis and perfusion-weighted MRI". Clinical Radiology, 65(1), 15-20.en_US
dc.identifier.issn0009-9260-
dc.identifier.urihttps://doi.org/10.1016/j.crad.2009.09.005-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S000992600900347X-
dc.identifier.urihttp://hdl.handle.net/11452/22692-
dc.description.abstractAIM: To evaluate the value of morphometric analysis and perfusion-weighted magnetic resonance imaging (MRI) in differentiating solitary metastases from high-grade gliomas. MATERIALS AND METHODS: Forty-eight tumours (22 high-grade gliomas and 26 solitary hemispheric metastases) were evaluated using conventional and perfusion-weighted MRI. T2-weighted, gradient-echo, echo-planar sequences were used for perfusion-weighted MRI. Relative cerebral blood volume (rCBV) ratios were calculated by dividing the rCBV of the intratumoural and peritumoural areas with the average CBV value of the normal white matter areas. Morphometric analysis was carried out by proportioning the area of peritumoural oedema to the mass area. Mann-Whitney U test and ROC Curve analysis were applied for statistical analysis. P < 0.05 was accepted as statistically significant. RESULTS: Mean rCBV ratios of intratumoural areas of high-grade gliomas and metastases were 5.02 +/- 2.47 and 4.62 +/- 2.46, respectively. No statistically significant difference was found (p = 0.515). rCBV ratios of peritumoural oedema were 0.89 +/- 0.51 in high-grade gliomas and 0.31 +/- 0.12 in metastases. The difference was statistically significant (p < 0.001). According to the results of morphometric analysis, a statistically significant difference was present between the two tumour types (p < 0.001). CONCLUSION: Measuring the oedema: mass and rCBV ratios of the oedema surrounding the tumour prior to operation in solitary masses proved to be useful for differentiating metastases from high-grade gliomas.en_US
dc.language.isoenen_US
dc.publisherWB Saundersen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBlood-volume mapsen_US
dc.subjectBrain-tumorsen_US
dc.subjectGlioblastoma-multiformeen_US
dc.subjectDiagnosisen_US
dc.subjectLesionsen_US
dc.subjectEdemaen_US
dc.subjectRadiology, nuclear medicine & medical imagingen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBrain edemaen_US
dc.subject.meshBrain neoplasmsen_US
dc.subject.meshCarcinoma, renal cellen_US
dc.subject.meshCerebrovascular circulationen_US
dc.subject.meshDiagnosis, differentialen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlioblastomaen_US
dc.subject.meshGliomaen_US
dc.subject.meshHumansen_US
dc.subject.meshImage interpretationen_US
dc.subject.meshComputer-assisteden_US
dc.subject.meshMagnetic resonance angiographyen_US
dc.subject.meshMaleen_US
dc.subject.meshMidlle ageden_US
dc.subject.meshRetrospective studiesen_US
dc.subject.meshSensitivity and specificityen_US
dc.subject.meshYoung adulten_US
dc.titleSolitary metastases and high-grade gliomas: Radiological differentiation by morphometric analysis and perfusion-weighted MRIen_US
dc.typeArticleen_US
dc.identifier.wos000273961400003tr_TR
dc.identifier.scopus2-s2.0-71849109940tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-3425-0740tr_TR
dc.identifier.startpage15tr_TR
dc.identifier.endpage20tr_TR
dc.identifier.volume65tr_TR
dc.identifier.issue1tr_TR
dc.relation.journalClinical Radiologyen_US
dc.contributor.buuauthorHakyemez, Bahattin-
dc.contributor.buuauthorErdoğan, Cüneyt-
dc.contributor.buuauthorGökalp, Gökhan-
dc.contributor.buuauthorDuşak, Abdürrahim-
dc.contributor.buuauthorParlak, Müfit-
dc.contributor.researcheridAAI-2336-2021tr_TR
dc.contributor.researcheridAAI-2318-2021tr_TR
dc.contributor.researcheridA-7826-2019tr_TR
dc.identifier.pubmed20103416tr_TR
dc.subject.wosRadiology, nuclear medicine & medical imagingen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ3en_US
dc.contributor.scopusid6602527239tr_TR
dc.contributor.scopusid8293835700tr_TR
dc.contributor.scopusid8312505100tr_TR
dc.contributor.scopusid6507393726tr_TR
dc.contributor.scopusid7003589220tr_TR
dc.subject.scopusCerebral Blood Volume; N Acetylaspartic Acid; Glioblastomaen_US
dc.subject.emtreeContrast mediumen_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBrain blood volumeen_US
dc.subject.emtreeBrain edemaen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeContrast enhancementen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeGliomaen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMetastasisen_US
dc.subject.emtreeMorphometricsen_US
dc.subject.emtreePerfusion weighted imagingen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeSensitivity and specificityen_US
dc.subject.emtreeWhite matteren_US
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