1. Açık Erişim@BUU
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Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/22636
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dc.contributor.authorYılmaz, Orhan-
dc.contributor.authorÇabalar, Mehmet-
dc.date.accessioned2021-11-12T12:33:38Z-
dc.date.available2021-11-12T12:33:38Z-
dc.date.issued1999-
dc.identifier.citationYılmaz, O. vd. (1999). "The in vivo and in vitro comparative nephrotoxicity of cefazolin and gentamicin". Veterinary and Human Toxicology, 41(4), 222-225.en_US
dc.identifier.issn0145-6296-
dc.identifier.urihttp://hdl.handle.net/11452/22636-
dc.description.abstractBiochemical, histopathological and cell culture evaluations compared the nephrotoxicity of cefazolin with that of gentamicin. New Zealand rabbits were dosed with 250 mg cefazolin/animal im twice daily, 3 mg gentamicin/kg im twice daily, or 0.9% NaCl solution for 10 d. The rabbits in drug-treated groups had necrosis of proximal kidney tubules and elevated urinary-gamma glutamyl transferase (uGGT) levels. The results of the histopathological examinations, uGGT analyses and effects in cell culture indicated the nephrotoxicities of both antibiotics were similar.en_US
dc.language.isoenen_US
dc.publisherComparative Toxicology Laben_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectToxicologyen_US
dc.subjectVeterinary sciencesen_US
dc.subjectGamma-glutamyl-transferaseen_US
dc.subjectCephalosporinen_US
dc.subjectDogsen_US
dc.subjectRatsen_US
dc.subjectAnimaliaen_US
dc.subjectOryctolagus cuniculusen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCattleen_US
dc.subject.meshCefazolinen_US
dc.subject.meshCells, cultureden_US
dc.subject.meshCephalosporinsen_US
dc.subject.meshGentamicinsen_US
dc.subject.meshKidneyen_US
dc.subject.meshRabbitsen_US
dc.titleThe in vivo and in vitro comparative nephrotoxicity of cefazolin and gentamicinen_US
dc.typeArticleen_US
dc.identifier.wos000081641900007tr_TR
dc.identifier.scopus2-s2.0-0032794441tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Veterinerlik Fakültesi/Patoloji Anabilim Dalı.tr_TR
dc.identifier.startpage222tr_TR
dc.identifier.endpage225tr_TR
dc.identifier.volume41tr_TR
dc.identifier.issue4tr_TR
dc.relation.journalVeterinary and Human Toxicologyen_US
dc.contributor.buuauthorÖzbilgin, Selda-
dc.relation.collaborationYurt içitr_TR
dc.identifier.pubmed10434375tr_TR
dc.subject.wosToxicologyen_US
dc.subject.wosVeterinary sciencesen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ2 (Veterinary sciences)en_US
dc.wos.quartileQ4 (Toxicology)en_US
dc.contributor.scopusid57225240619tr_TR
dc.subject.scopusGentamicins; Nephrotoxicity; Aminoglycoside Antibiotic Agenten_US
dc.subject.emtreeCefazolinen_US
dc.subject.emtreeGamma glutamyltransferaseen_US
dc.subject.emtreeGentamicinen_US
dc.subject.emtreeSodium chlorideen_US
dc.subject.emtreeAnimal cellen_US
dc.subject.emtreeAnimal experimenten_US
dc.subject.emtreeAnimal modelen_US
dc.subject.emtreeAnimal tissueen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCytopathologyen_US
dc.subject.emtreeDrug induced diseaseen_US
dc.subject.emtreeHistopathologyen_US
dc.subject.emtreeIn vitro studyen_US
dc.subject.emtreeIn vivo studyen_US
dc.subject.emtreeKidney cell cultureen_US
dc.subject.emtreeKidney necrosisen_US
dc.subject.emtreeKidney proximal tubuleen_US
dc.subject.emtreeNephrotoxicityen_US
dc.subject.emtreeNonhumanen_US
dc.subject.emtreeRabbiten_US
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