Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/21912
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dc.date.accessioned2021-09-13T12:29:37Z-
dc.date.available2021-09-13T12:29:37Z-
dc.date.issued1997-
dc.identifier.citationGürpınar, A. N. vd. (1997). "Fluconazole treatment of neonates and infants with severe fungal infections". Journal of International Medical Research, 25(4), 214-218.en_US
dc.identifier.issn0300-0605-
dc.identifier.urihttps://doi.org/10.1177/030006059702500408-
dc.identifier.urihttps://journals.sagepub.com/doi/10.1177/030006059702500408-
dc.identifier.urihttp://hdl.handle.net/11452/21912-
dc.description.abstractA total of 24 neonates and infants, aged from 2 days to 10 months, received treatment with intravenous fluconazole for microbiologically documented or presumed fungal infection. The mean fluconazole dosage was 6 mg/kg/day (range 2 -16 mg/kg/day) and the mean duration of therapy was 25 days (range 5 - 72 days). Efficacy was evaluated in neonates with proven fungal infections, as documented by the presence of pathogen at baseline. A positive clinical response was achieved in 23 of the 24 clinically evaluable patients (96%); eradication of the fungal organism was also achieved in 23 of the 24 evaluable patients (96%). Adverse events occurred in two patients (8%) but therapy was not discontinued in either patient. The present results confirm the efficacy and safety of fluconazole in the treatment of neonates and infants with severe fungal infections.en_US
dc.language.isoenen_US
dc.publisherSage Publicationsen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectResearch & experimental medicineen_US
dc.subjectPharmacology & pharmacyen_US
dc.subjectFluconazoleen_US
dc.subjectAntifungal therapyen_US
dc.subjectCandida albicansen_US
dc.subjectFungal infectionen_US
dc.subjectNeonateen_US
dc.subjectInfanten_US
dc.titleFluconazole treatment of neonates and infants with severe fungal infectionsen_US
dc.typeArticleen_US
dc.identifier.wosA1997XT23300008tr_TR
dc.identifier.scopus2-s2.0-0030768526tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Cerrahisi Anabilim Dalı.tr_TR
dc.identifier.startpage214tr_TR
dc.identifier.endpage218tr_TR
dc.identifier.volume25tr_TR
dc.identifier.issue4tr_TR
dc.relation.journalJournal of International Medical Researchen_US
dc.contributor.buuauthorGürpınar, Arif Nuri-
dc.contributor.buuauthorBalkan, Emin-
dc.contributor.buuauthorKılıç, Nizamettin-
dc.contributor.buuauthorKiriştioğlu, İrfan-
dc.contributor.buuauthorAvşar, İzzet-
dc.contributor.buuauthorDoğruyol, Hasan-
dc.contributor.researcheridAAI-3656-2021tr_TR
dc.identifier.pubmed9283996tr_TR
dc.subject.wosMedicine, research & experimentalen_US
dc.subject.wosPharmacology & pharmacyen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ4en_US
dc.subject.scopusInvasive Candidiasis; Fluconazole; Systemic Mycosisen_US
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